RESEARCH
Guillermo Serrano, Ph.D., is a Postdoctoral Researcher at the King Abdullah University of Science and Technology (KAUST), specializing in computational biology and bioinformatics. His research primarily focuses on single-cell genomics and gene regulatory networks, with applications in understanding cancer and stem cell biology. He has conducted pancancer analyses to study the deregulation of long non-coding RNAs (lncRNAs) and investigated the roles of specific histone variants in human embryonic stem cell development. Additionally, he has explored the genetic basis of behavior in honeybees, showcasing the diversity of his interests. In disease and therapy, he has studied age-related and disease-specific changes in hematopoietic progenitor cells, researched therapeutic targets for myelodysplastic syndromes, and contributed to optimizing CAR T cell therapy for multiple myeloma. Recently, he has been investigating the roles of specific histone variants in human embryonic stem cell (hESC) development, using both single-cell and bulk sequencing to understand their impact on gene expression and chromatin organization.

BIOGRAPHY
Guillermo Serrano earned his Ph.D. in Computational Biology from the University of Navarre (Spain), following an MSc in Bioinformatics from the University of Valencia and a BSc in Biology with a specialization in Biotechnology from the University of Alicante. He joined the King Abdullah University of Science and Technology (KAUST) as a Postdoctoral Researcher in 2023, where he explores the role of histone linkers in early human cell development and their implications in oncology. Previously, he conducted postdoctoral research at Tecnun, University of Navarre, developing machine learning and deep learning tools for omics data analysis and drug repurposing, with a focus on oncohematological diseases. His research centers on single-cell genomics and gene regulatory networks, contributing to advancements in cancer biology, stem cell development, and therapeutic optimization, with over 20 peer-reviewed publications in prestigious journals such as Nature Communications, Bioinformatics, and Science Advances. Passionate about mentoring, he has a strong track record of guiding Ph.D. and master’s students, fostering their growth in computational biology and bioinformatics.